One of Sydney's most famous restaurants will close at the end of the year with the chef and owner of Guillaume at Bennelong confirming he would not re-tender for the eatery's Opera House site.

Guillaume Brahimi cited conflicting visions between himself and the Opera House Trust.

The restaurant space was put out to tender for the first time in a decade in May. Applications closed on Tuesday.

''Our goal was always to run one of the best restaurants in the country, befitting such an iconic venue. The Opera House Trust is now seeking a bistro style restaurant, cafe and bar. This clearly involves a very different vision,'' Brahimi said.

''I accept their vision but my vision 12 years ago was to have a fine dining restaurant and to try to be the best at what I do. ''

The restaurant, which was awarded two hats in The Sydney Morning Herald Good Food Guide 2013, will operate as normal until the end of the year, when the existing lease ends.

Brahimi said the decision was not difficult, although it was an emotional time for himself and his staff. ''It's the right decision. I will miss Bennelong … But missing is OK. There is no regret,'' he said.